Sentence examples for derived toxicants from inspiring English sources

Linking exposures to chemical, physical, or biologically derived toxicants in the environment to clinical outcomes in humans continues to be a research focus for the NIEHS.

Furthermore, these exogenously derived toxicants could interact synergistically with endogenous unsaturated aldehydes and thereby accelerate the onset and development of atherosclerosis, diabetes, Alzheimer's disease, and other pathogenic conditions that have cellular oxidative stress as a molecular etiology.

Exposure to smoke-derived toxicants has been shown to lead to immune dysfunction [ 29].

A small group of compounds can act as mutagens, but the vast majority of nutritionally derived and environmental toxicants do not alter DNA sequence [ 2].

Heating tobacco significantly reduces levels of combustion-derived toxicants in the aerosol compared to cigarette smoke.

Here, we established the phylogenetic timing of disruptive UGT1A6 mutations and explored the hypothesis that gene inactivation in cats was enabled by minimal exposure to plant-derived toxicants.

The results also raise the question of what other drug-derived toxicants are out there, she says.

Sources of environmental stressors are understudied and largely limited to human-derived toxicants such as pesticides like rotenone.

However, people living in agricultural environs are often at a greater risk of developing neurodegenerative disorders that cannot be accounted for by human-derived toxicants alone.

These results suggest that sequestration of lipophilic coplanar PCBs to adipose tissue may contribute to AhR-mediated increases in TNF-α and the development of adipocyte insulin resistance, an effect manifest in lean conditions as well as during weight loss when adipose-derived toxicants may be liberated.

The present work established the chemical competence of the E. coli dioxygenase AlkB to oxidize and repair acrolein- and MDA-derived exocyclic guanine lesions, suggesting that one role of AlkB may be to alleviate the mutagenic and toxic consequences of reactive aldehydes derived from these primary toxicants.