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A scaling law is derived to elucidate the physical effects governing the characteristic nanostructure length scale of the twin width.
Three characteristic parameters, i.e. the critical initiation energy ΔGc, the shear band stability index k0, and the critical shear band length lc, are derived to elucidate the initiation and propagation of shear bands.
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Our approach involves leveraging innovative computational models for characterizing subclonal genomic cell populations and using single-cell data from primary tumors and patient-derived xenografts to elucidate the mechanisms presiding over tumor plasticity.
DOI: http://dx.doi.org/10.7554/eLife.06126.004 To reveal how ventral stress fibers are derived from arcs and to elucidate the mechanosensitive basis of this process, we examined the dynamics of the stress fiber network in U2OS cells, where all three stress fiber categories can be readily visualized by live-cell microscopy (Hotulainen and Lappalainen, 2006).
Since RNA molecules are complementary copies of the DNA from which they are derived, several laboratories have tried to elucidate a direct role of RNA as a template in DNA repair (Fig. 2).
We identified 1227 feline cDNA sequences derived from tissues obtained from ten cats and performed extensive comparative genomics functional analysis to elucidate the computationally derived comparative gene expression analysis patterns, biochemical functions and phenotypes associated with these sequences.
In this study, we derive a semi-analytical model to elucidate the transport of ions, heat and mass in air-breathing fuel cells.
We use real-time imaging of live cells, genome editing, genetics and biochemistry in human stem cells, in stem-cell derived organoids and in budding yeast to elucidate the molecular mechanisms that underlie highly dynamic actin-mediated membrane trafficking events.
The PanK1 isoform is highly and selectively expressed in liver, thus we derived a Pank1−/− mouse model to elucidate the role of this regulatory enzyme in the CoA response to fasting.
With respect to pathophysiological relevance of these receptors and the circuits that ligand-receptor pairs might produce, a great help to elucidate functions derives from the use of mice nullified for specific receptor subtypes.
It is proposed that statistical planning for the use of enzymes derived from nematophagous fungi is a viable way to elucidate some questions about their mechanism of action.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com