PubSub Core defines several other optional conformance classes (see Fig. 2), introducing additional functionalities, e.g. to pause a Subscription (Pausable Publisher), derive additional publications (Publication Manager), group messages in batches (Message Batching Publisher).
Specific PCR primer pairs for human CYP3A4 and CYP3A5 gene were derived from publication.
Downloadable data tables, for more convenient offline data analysis, are derived from publications and are current as of the time of publication.
Data on countries' public and private health research expenditures combined were derived from publications by Chakma et al 12 and Young et al, 13 14 and were available from 2007 to 2012 for Australia, Canada, China, Europe, India, Japan, South Korea and the USA.
The specific question addressed here is how much earlier hypotheses for compound target interactions can be formulated based on information from patents compared to using evidence derived from publications in scientific journals.
To address the question of how much earlier hypotheses for compound target interactions can be formulated based on information from patents compared to using evidence derived from publications in scientific journals, a reference list of compound target interactions was compiled.
As far as information derived from publications in scientific journals is concerned, there are now a number of well established databases in the public domain (e.g. ChEMBL [1]) that have widespread use when looking at compound target interactions.
Figures 1 and 2 summarise the findings in regards to the question of how much earlier hypotheses for the 130 compound target interactions in the reference set can be formulated based on information from patents compared to using evidence derived from publications in scientific journals.
For the majority (85%) of rare disorders presented in Table 2, data was derived from publications.
The scores are derived from publications and from genotype phenotype data.
Data pertaining to vaccine potential of the antigens was derived from publications describing global analyses of preselected antigens for their potential to induce an immunoprotective response [ 25, 95- 97].
