Here we describe in detail, the synthesis and gas storage properties of a series of porous polyimides (Tr-NPI, Tr-PPI, Tr-CPI, Td-PPI and Td-CPI) with various network topologies derived from polycyclic aromatic hydrocarbon linkers.
The authors of most reports on the quantification of multiple DNA adducts focused on different classes of adducts, for example, either hydrophobic "bulky adducts" derived from polycyclic aromatic hydrocarbons or hydrophilic adducts formed as a consequence of oxidative stress and internal exposure to degradation products of lipid peroxidation.
Cytochrome P450 1A1 (CYP1A1) is involved in the biotransformation of tobacco-derived polycyclic aromatic hydrocarbons (PAHs) into carcinogenic metabolites.
Thus, we speculated that the interaction between CYP1A1 or GSTM1 polymorphisms and lung cancer is related to polycyclic aromatic hydrocarbons exposure derived from smoking because polycyclic aromatic hydrocarbons are primarily metabolized by CYP1A1 and GSTM1.
These compounds can be synthesized by a variety of microorganisms (bacteria, yeasts and filamentous fungi) (Sanchez et al. 2007; Díaz De Rienzo et al. 2016) utilizing both water-immiscible hydrocarbons i.e., plant/animal derived oil, n-alkanes, polycyclic aromatic hydrocarbons (PAHs) and/or water-soluble compounds i.e., glucose, fructose, sucrose, xylose, galactose, mannitol, glycerol, ethanol.
DNA adducts derived from complex mixtures of polycyclic aromatic compounds emitted from tobacco smoke are compared to industrial pollution sources (e.g., coke ovens and aluminum smelters), smoky coal burning, and urban air pollution.
The dimensions and arrangements of aromatic rings (topology) in adducts derived from the reactions of polycyclic aromatic hydrocarbon (PAH) diol epoxide metabolites with DNA influence the distortions and stabilities of double-stranded DNA, and hence their recognition and processing by the human nucleotide excision repair (NER) system.
The chief product, polycyclic diketone 10, is derived from a double hetero-Diels Alder addition of 2 to 5. X-ray analysis of compound 8 shetero-Diels Alderxceptionadditionge pofycyclic aromatic arch, and the X-ray structure of 10 reveals it to be a chiral molecular tweezer.
Lcc are of particular interest with regard to potential industrial applications due to their ability to oxidize a wide range of toxic and polluting substrates, including polycyclic aromatic hydrocarbons (PAH) derived from petroleum, textile dyes and pesticides.
Preliminary evidence suggests that transplacental exposure to polycyclic aromatic hydrocarbons (PAHs) derived largely from traffic-related air pollutants may be a risk factor for the early development of asthma-related symptoms in this cohort [5].
