Evaluation of preparations derived from implants in various types of tissues indicates homogeneous degradation and only limited gas formation during in vivo testing.
To facilitate nervous system repair and improve functional outcomes, clinicians and researchers are utilizing therapies that provide proregenerative cues and structural support using exogenous extracellular matrix (ECM) derived neurological implants.
Based on the anticonvulsant and neuroprotective properties of adenosine, and based on the long-term survival potential of stem cell derived brain implants, adenosine releasing stem cells may constitute a novel tool for the treatment of epilepsy.
The ultimate measure of such effects will be a comparison of long-term survival rates derived from implants, compared to conventional, mark re-sight techniques [ 6, 7].
The activation of the NLRP3 inflammasome has been implicated in driving inflammatory responses to nanoparticular carbon [ 251] and polystyrene [ 252], as well as nanodebris typically derived from implants [ 253] including amorphous silica and titanium dioxide (TiO2) [ 254], CoCrMo [ 255], and silver [ 256] (reviewed in [ 257]).
There was only one implant in each bone sample while CBCT scanning, which means the beam-hardening artefacts derived from multiple implants in the ROI (i.e., number of implants and corresponding spatial distribution) are not considered.
Capsule tissues from both smooth and textured implants were compared, although the majority of the samples were derived from smooth implants.
Engineered implants derived from neonatal rabbit chondrocytes and collagen type I hydrogel, were loaded in dialyzer pockets and implanted in muscle and articular cavity of rabbits to simulate different stress and tissue fluid micro-environments.
It is well recognized that wear particles derived from orthopaedic implants have the potential to induce inflammation, which may eventually lead to aseptic loosening of the artificial joint.
Accordingly, alloplastic implants derived from polymers and ceramics, usually in preformed shapes, have been favored in facial augmentation for aesthetic purposes [ 5, 8– 14].
