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Using amino acid based MSAs and comparing between evolutionary and similarity-based MSAs may reduce error, and advanced filtering methods such as GUIDANCE may also help, particularly for divergent sequences where k-mer derived guide trees may become unstable.
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Alignment certainty was quantified using the pair Hidden Markov Model framework implemented in ZORRO (Wu et al., 2012), using FastTree to derive guide trees for each alignment.
This concept is taken as a normative basis to provide a first orientation regarding energy technologies and to derive guiding principles which can be used to develop assessment criteria and indicators ("Sustainability principles for energy technology assessment" section).
Quantitative structure activity relationship (QSAR) model is derived to guide the further lead optimization.
Additionally, standardized numerical formulae of the dimensionless stress intensity factor have been derived to guide the engineering application.
A residual-based posteriori error estimator using RPHT-splines basis functions is derived to guide the local refinement process adaptively.
So the explicit development controls have been derived to guide and organize at micro level so as to achieve the macro level considerations of ecological integrity.
An economic model is thus derived to guide such a sale; here the CDN requesting resources (buyer) and the CDN offering resources (seller) agree on the quantity and the price by means of a utility-based negotiation approach.
Function formulas in first order predicate logic form are derived to guide in constructing the hierarchical multistage BIN.
Although each method has distinct advantages, they also each have limitations, and it is important for the clinician to understand the strengths and limitations of the method employed in order to utilize the information derived to guide acute resuscitation effectively [ 10].
Fifth, a common vocabulary will be developed to describe nuclear features and biophysically derived principles guiding chromosome folding.
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CEO of Professional Science Editing for Scientists @ prosciediting.com