# Contextual measures were derived using postal code information, from which indices at the relevant level of aggregation could be geocoded; SEIFA, Socio-Economic Indexes for Areas; LGA, Local government area.
However, many simple methods, from which indices can be derived, have been assessed and validated e.g. homeostasis model assessment (HOMA), quantitative insulin sensitivity check index (QUICKI).
This index is derived from the Handedness Index [45], which has also been used in studies on auditory laterality (e.g. [26], [27]).
In critically ill patients, many CCR-related parameters (oxygen consumption, stroke work, cardiac power …) have been studied, most of which are derived from cardiac index (CI) magnitude during a dobutamine test [ 6].
The most common are the KC prediction index (KPI), which is derived from eight quantitative indices and the KC Index (KCI %) itself derived from the KPI and four other indices [ 42], and the KISA % which is based on keratometric value, inferior-superior asymmetry (I-S), asymmetric bow-tie astigmatism (AST), and skewed radial axis (SRAX) values [ 43].
While education grouping was on an absolute basis i.e. the highest level of education attainment, irrespective of country of residence wealth quintiles were derived from the asset index, which scored the relative position of each household comparing to others within each country.
The cutoff value was 0.85 for survival and metastasis, which was derived from the Youden index.
The result of the 70-gene signature is presented as a binary result (good or poor prognosis), which is derived from an index-score (−1 to 1) [ 9, 10].
We observe the strong presence of information derived from the hydrophobicity indices, which agrees with the observations in Goh et al. (2004), Overton and Barton (2006), Chen et al. (2007), Overton et al. (2008), Kurgan et al. (2009) and Babnigg and Joachimiak (2010).
r [ 41 ] is an index derived from the correlation index D Lewontin [ 39, 13, 40 ].
The defined daily doses (DDD) are based on the official ATC-Index for Germany 2010 [ 17], which is derived from the WHO-index 2010 [ 18]. "Symptom-free" is defined as a total symptom score of 0. The primary analysis will be based on the results of two statistical tests.
