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As for the images in Figure 1C D, we note that these were not derived from the screen.
For instance, unbiased screens may be followed up by detailed mechanistic confirmations of a hypothesis or of findings derived from the screen.
It is interesting that all of the promoters derived from the screen have a cytidine to thymidine substitution at position -9 and a thymidine to adenosine substitution at position -8.
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For each subject the DER were calculated by multiplying the basal metabolic rate (BMR) by the appropriate physical activity factor (1.5 1.8, derived from the screening questionnaire, [26]).
Bioactivity profiles were derived from the screening results contained in the NCI-60 dataset.
In case suspect samples (based on the in-house microbiological screening assay) were analysed, the indicative values derived from the screening assay were used to determine standard addition levels.
We also considered a loss of QALYs due to the anxiety derived from the screening mammogram itself (7 days at 25% of the healthy state) and from a false positive result (25 days at 25% of the healthy state).
Hence, a positive response of 1 or more of any of the indicator questions on RSD derived from the screening tool was collapsed into a single variable of one or more indicators of relative social disadvantage (1+ RSD) for analysis.
Information on each individual woman (age at diagnosis, BI-RADS category, final TNM classification [UICC 2002], the type of diagnostic work-up and final diagnosis) was derived from the screening registry and cancer registry.
An effective screening approach has consisted in the use of mechanism-based profiling using the S. aureus fitness test-based genome-wide screening for upfront empiric evaluation of the antimicrobial activities derived from the screening of microbial product libraries on a wide panel of bacterial pathogens [ 66].
The borehole flow data indicate that during pumping conditions about 40% of the groundwater produced by the well is derived from the well screen below 200 mbls, while 60% is derived from the well screen above 175 mbls.
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