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There is potential economic benefit (as well as scientific reputation) to be derived from discoveries made from human tissues exported from the developing world.
It should be mentioned that academic institutions are also vested in intellectual property concerns, as most prominent universities have a very keen sense of value that can be derived from discoveries made by their own scientists and have resources in place to protect those discoveries.
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As such it carries with it history from several disparate fields of research including a strong tradition in deductive reasoning primarily derived from discovery focused molecular biology and physics.
Recently, several companies have begun marketing so-called personal genomic tests directly to consumers; these tests are derived from discovery research and are offered with the implicit purpose of guiding health risk assessment and disease prevention (26).
The sequences of miRNA deposited in miRBase are derived from discovery studies in which many strict miRNA verification criteria were applied (e.g. hairpin forming potential, evolutionary conservation, presence in multiple clones/sequence reads or homogeneity of the 5'end).
Scientists always have intellectual and financial conflicts of interest that bias them to exaggerate the potential benefits to be derived from their discoveries and to minimize the potential risks.
However, the clinical use of diagnostic tests derived from these discoveries is lagging behind.
Primarily, this was an investigation of a single disease (schizophrenia) where the SNPs derived from the discovery sample were tested in an independent schizophrenia replication sample.
As an example, a polygenic score derived from a discovery sample from consortium data in schizophrenia was applied to seven different target samples: One bipolar cohort and six other non-neuropsychiatric cohorts [9].
A very recent U.S. Supreme Court decision clarified one of the larger questions for such research: by protecting knowledge derived from the discovery of such natural processes from the exclusivity of patent protection, while nonetheless permitting "ownership" of processes invented or synthesized from them for manufacture and application as vaccines or medicines beneficial to human health.
Derived from false discovery-rate correction of p-values.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com