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However, IL-8 and MCP-1 scatter plots suggested there was a positive correlation between data derived from both platforms.
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Mr. Marchionne said that a few Chrysler car models, mostly derived from Fiat platforms, would be delayed as a result.
However, signatures derived from other platforms were not demonstrated to work with CMAP.
Identity of genes was determined by BLAST program when gene signatures were derived from different platforms.
Several studies have demonstrated that pooling data derived from different platforms is a complex task with numerous pitfalls [ 2, 3].
Altogether 16 time series datasets (Additional file 4) containing 384 samples derived from 5 platforms fulfilled the set criteria.
Second, comparing datasets derived from different platforms, and from samples provided by various centers, is intrinsically prone to systematic batch effects that need to be carefully monitored.
As it is highly problematic to combine expression data derived from different platforms, functional groups were identified separately for each of the three expression sets.
The MAQC landmark multi site study focused on the ability to capture global differences by different platforms and in intra platform reproducibility and sensitivity, but did not address how to integrate data derived from different platforms [ 41, 42].
Finally, the uniquely aligned probe set)s derived from all platforms were intersected with Ensembl R72 transcriptome using BEDtools [ 22] to obtain Ensembl gene ID, transcript ID, exon ID, and corresponding RefSeq gene names for each probe set).
However, many are likely the result of experimental errors, especially when the data are derived from sequencing platforms that are prone to introducing indels at high rates in photopolymer tracts.
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