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They also have the aptitude to scavenge oxygen-nitrogen derived free radicals by donating hydrogen atom or an electron, chelating metal catalysts and activating antioxidant enzymes [8, 9].
They have the aptitude to scavenge oxygen-nitrogen derived free radicals by donating hydrogen atom or an electron, chelating metal catalysts, activating antioxidant enzymes and inhibiting oxidizes [4 6].
Oxygen derived free radicals are very important mediators of cell injury.
SOD provides the first line of defense against oxygen derived free radicals [ 6].
In addition, alcohol develops ulceration by producing toxic oxygen derived free radicals [ 56].
Malondialdehyde (MDA) is an end product of peroxidation of cell membrane lipids caused by oxygen derived free radicals.
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In hematophagous insects, blood meal-derived free heme is a strong pro-oxidant and can tax the midgut antioxidant system.
The free radical theory of aging hypothesizes that oxygen-derived free radicals are responsible for the age-related damage at the cellular and tissue levels.
In addition, LDL-derived free cholesterol may move to the plasma membrane without transiting to LE/LY since acid lipase is also present in early endocytic organelles [2].
It is widely accepted that the pathogenesis of gastric mucosal lesions involves oxygen-derived free radicals.
Microglia-derived free radicals were major factors that bridged neuroinflammation and α-syn dysfunction in mediating chronic PD neurodegeneration.
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