Using this biodiversity derived discovery approach, Tr. anilis and T e. subulata were selected for venom characterization, as they are representatives of a clade that has a similar venom apparatus to that of cone snails and produce venom peptides to subdue their prey.
It should be mentioned that academic institutions are also vested in intellectual property concerns, as most prominent universities have a very keen sense of value that can be derived from discoveries made by their own scientists and have resources in place to protect those discoveries.
There is potential economic benefit (as well as scientific reputation) to be derived from discoveries made from human tissues exported from the developing world.
As such it carries with it history from several disparate fields of research including a strong tradition in deductive reasoning primarily derived from discovery focused molecular biology and physics.
Recently, several companies have begun marketing so-called personal genomic tests directly to consumers; these tests are derived from discovery research and are offered with the implicit purpose of guiding health risk assessment and disease prevention (26).
The sequences of miRNA deposited in miRBase are derived from discovery studies in which many strict miRNA verification criteria were applied (e.g. hairpin forming potential, evolutionary conservation, presence in multiple clones/sequence reads or homogeneity of the 5'end).
Scientists always have intellectual and financial conflicts of interest that bias them to exaggerate the potential benefits to be derived from their discoveries and to minimize the potential risks.
In reality, the public and private sector work hand-in-hand, relying on the discoveries derived from basic scientific research to develop the next blockbuster drug or medical device that could relieve the suffering of millions of patients; one cannot thrive without the other.
However, the clinical use of diagnostic tests derived from these discoveries is lagging behind.
In the 1970s, many voices argued that yeast, specifically S. cerevisae, is well suited as a model eukaryote to expand the discoveries derived from phage and prokaryotic studies (for review see Hall and Linder 1993).
Because we were testing 50 modules at the same time, the p values generated by the test were further adjusted using the Benjamini and Hochberg correction [ 31] to derive False Discovery Rates (FDRs).
