Complementary two-dimensional (2D) and three-dimensional (3D) Quantitative Structure Activity Relationship (QSAR) techniques were used to derive a preliminary model for the dopamine transporter (DAT) binding affinity of 80 racemic threo-methylphenidate (MP) analogs.
We present three exemplar techniques (sphere-casting refined by QUAD menu (SQUAD), discrete zoom, and continuous zoom) and derive a preliminary design space for progressive refinement from their characteristics.
The comprehensive literature review is conducted to derive a preliminary grid of drivers to be presented for focus groups' discussion in order to identify a clustering of main drivers of change capable of significantly influencing geo-economical scenarios [55] in the field of logistics at a global level [13, 18, 26].
This analysis was performed to check data availability and derive a preliminary estimate of disability-adjusted life years (DALYs) due to mercury use in ASGM in Zimbabwe.
We derived a set of preliminary codes from literature which was agreed upon by all research partners.
The following paper reports on some of the pedagogical issues that have been derived from a preliminary review and roundtable participants' experiences with CAAD curricula.
The analyses were performed on a set of 170 patients derived from a preliminary analysis and enriched in superinfection cases.
The sampling time was 20 h, derived from a preliminary experiment, aiming at avoiding saturation of the SPR-IDA resin with metal cations.
With an assumed rate of 18% protocol violations (derived from a preliminary retrospective analysis of 100 patients), the calculated total sample size was 152 patients (76 patients per arm).
The results derived from preliminary experiments on a laboratory scale mill shows satisfactory agreement between the actual measurement and the simulated acoustic signal.
