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If successful for cystic fibrosis, the same general strategy of yeast phenomic modeling should be applicable to derive understanding about disease complexity involving any conserved cellular pathway.
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The aim is to try to derive understanding from the world around us and then use that understanding to feed back into design.
The availability of both genomic and transcriptomic data for a large number of bacterial organisms (http://www.ncbi.nlm.nih.gov/genome/browse/) provides unprecedented opportunities for researchers to derive novel and deeper understanding about what determines the organization of the genomic information (such as operons and associated regulatory systems) in a genome.
These socioculturally derived understandings are inevitably reflected in their reporting.
Current understanding about restraint use derives mostly from acute and long-term residential settings.
Significant understanding about chemotaxis has been derived from research on the social amoeba Dictyostelium discoideum.
Familiarity with BLAST is also crucial for an entry-level understanding about gene annotations and deriving information about new genes.
Most of our understanding about perinatal GC development derives from rodents, in which all gonocytes (undifferentiated GC) co-ordinately lose expression of the pluripotency factor OCT4 and stop proliferating in late gestation.
Most of our understanding about regulation of GC development and differentiation derives from rodents while relatively little is known in primates.
It aims to build understanding about how and why health is integrated into foreign policy and derive lessons of potential relevance to other nations interested in developing whole-of-government global health strategies.
To gain a clearer understanding about the susceptibility of patient tumours to TRAIL and FASL, we derived primary human cancer epithelial cells from colon cancer patients.
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CEO of Professional Science Editing for Scientists @ prosciediting.com