The constants in Equations (4a)–(4d) are nondimensional composites of dimensional parameters of the full system, derived in the Additional file 1: Supplementary Model.
The derived analytical expressions address the full system, including light source, optical waveguide and the detection unit and can serve as a tool for TIRF-system design.
In [ 18], we derive the association rate for the full system as (4) k assoc = 1 t R T F bound T F free · A i max A i total where t R is the residence time of a molecule on the DNA, T Ffree the number of free molecules and A i max / A i total the ratio of free DNA.
Remember that a full system configuration should be derived from the partial configuration.
In the limit as ε → 0 of system (6), we derive the layer problem, which approximates the fast components ( v, m, h, n ) of the full system dynamics: δ v ˙ = f 1 ( v, m, h, n, w, s ), δ m ˙ = f 2 ( v, m ), h ˙ = f 3 ( v, h ), n ˙ = f 4 ( v, n ), w ˙ = 0, s ˙ = 0, (7).
The full system was installed in Sept. 2014.
Solving the full system, i.e., Eqs.
We simulated the full system in Eqs.
Instead of the full system of Eqs.
defer.add img); Schedule periodic full system scans.
