Sentence examples for derivatives targeting from inspiring English sources

A series of novel tertiary amine derivatives targeting CXCR4 were designed, synthesized, and evaluated.

In this study, we have synthesized different diaryl urea derivatives targeting the inhibition of mycolic acid biosynthesis.

Herein, we report the synthesis and agonistic activities of a series of indolizine derivatives targeting to α7 nAChR.

In the present study, a series of novel 6-substituted diarylpyridine derivatives targeting the entrance channel of the NNIBP of RT were designed through a molecular hybridization strategy.

In addition, the brief SARs, structural modifications of NBD-556 and its derivatives targeting the "Phe-43 cavity" as CD4 mimics were also described.

This complex structure reveals the interactions between TPI1 and tubulin, and thus provides insights into the development of new anthracenone derivatives targeting the colchicine binding site.

A brief overview is given of previous efforts to design simplified aminoglycoside derivatives targeted at the bacterial decoding site RNA.

In previous studies (Janjetovic et al, 2009, 2010), we established that vitamin D derivatives target the NF- κB pathway in human keratinocytes.

Transgenic constructs were designed to express ArcLight and various derivatives targeted to the plasma membrane and nuclear membranes of Arabidopsis root cells.

However, on the basis of circular dichroism, fluorescence, and absorption spectral analysis, Feng et al. unequivocally determined that AMI-1, and related naphthalenesulfonate derivatives, target the substrate instead of the PRMT enzyme and are therefore not direct PRMT inhibitors.

In view of former findings for ArcLight in mammalian cells showing large shifts in fluorescence intensity in response to voltage changes [ 11, 12], we have assembled and introduced into Arabidopsis constructs encoding ArcLight and several derivatives targeted to the plasma membrane and nuclear membranes of root cells.