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In a mouse ascending urinary tract infection model with E. coli CFT073 as pathogen, two doses of intravenous, subcutaneous or oral treatment with the Pip-pyrr-MeArg derivative reduced the bacterial counts in the kidneys, bladder and urine to varying levels.
A polymerizable, PEGylated vancomycin derivative reduced biofilm attachment but resulted in inferior cement mechanical properties.
Minocycline, a tetracycline derivative, reduced Mmp-9 protein amounts in Fmr1 −/y mice and improved behavioral and dendritic spine defects (Bilousova et al., 2009; Dansie et al., 2013; Rotschafer et al., 2012).
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A quicker degree reduction means a lower data complexity in cryptanalysis, which can be determined by fast point at which the derivative reduces the degree at least 2.
Further enhancement in method performance is obtained by basing the stencils on generalizations of Padé approximation, or generalized definitions of the derivative, reducing spurious dispersion, anisotropy, and reflection, and by improving the representation of source terms.
Indeed, for (beta=0), this derivative reduces to the Hadamard fractional derivative, and when (beta=1), we recover the Caputo-Hadamard fractional derivative.
(6) Moreover, for (z(t)=t) and (w(t)=1), the generalized fractional derivative reduces to the Caputo fractional derivative as bigl( ^{c}D^{alpha }_{a+}u bigr) (t) = frac{1}{Gamma (2-alpha)} int^{t}_{a} (t-s)^{1-alpha }u"(s),ds.
Artemether (ARTM) which is artemisinin derivative reduces malaria transmission and may also reduce the gametocyte carriage [ 4, 5].
The step-wise linear approximation using the Fréchet derivative reduces the problem to one of finding the minimum of a quadratic function.
Although the charges incorporated on the cellulose derivative reduce the tendency of the copolymer to form large clusters, especially at high polymer concentrations, the charges do not protect the molecules from forming interchain associations.
The Helsinki Heart Study tested whether treatment with gemfibrozil (a fibric acid derivative) reduces the incidence of coronary heart disease (CHD) in middle-aged, dyslipidaemic men, the volunteers for which were selected from men aged 40 55 years, employed by two government agencies and five industrial companies, and living in different parts of Finland.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com