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Therefore, this derivative constitutes a new lead compound which can be used as a starting point to improve the design of non-toxic Pgp modulators.
This derivative constitutes an interesting building block for further modification towards new-to-nature sophorolipids with high potential for self-assembly applications.
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Therefore, an INP derivative constituting the N- and C-terminal domains is used to display foreign proteins on the surface of E. coli (Jung et al. 1998; Lee et al. 2000; Shimazu et al. 2001a; Cho et al. 2002; Kang et al. 2003; Li et al. 2004; Wu et al. 2006b; Yim et al. 2006).
The use of furan derivatives constitutes an additional positive feature in this context, because of their renewable character.
Tetramic acid derivatives constitute an important class of nitrogen containing heterocycles, and are key structural motifs in many natural products of terrestrial and marine origin.
Poly(pyrrole), [PPY]; poly aniline) [PANI]; poly(thiophene), [PTH] and its derivatives constituted the polymer component; PTH was prepared from the monomers bithiophene, terthiophene, 3-methylthiophene and 2,5-dimethylthiophene.
Next to sugars also sugar derivatives constitute an important building block of natural fibers and are therefore readily available.
The resulting temporal sequence of the 27 features, along with their first and second temporal derivatives constitute the feature set for the audio modality.
The resulting temporal feature vectors, which correspond to the four different TMA energies, along with their first and second temporal derivatives constitute the feature set for the visual modality.
Similar to the feature parameter settings for the Aurora-2 database, the resulting 13 new features plus their first- and second-order derivatives constitute the finally used 39-dimensional feature vector.
Since Delta toxin recognizes a specific receptor identified as the ganglioside GM2, this toxin and recombinant derivatives constitute valuable tools in cell biology and therapeutic agents, for example in identifying and treating cancer cells overexpressing GM2. C. perfringens Delta toxin was produced and purified as previously described [2].
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