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Most prognostic (n = 11/15) and all prescriptive (n = 11) CPRs have not progressed beyond the derivation stage of development.
The presence of high concentrations of LIF is dispensable after the derivation stage, and conditioned medium/embryonic feeders alone are sufficient to keep the cells undifferentiated.
Data from the rule derivation stage of the task were also examined using whole-brain analysis.
50 51 While some decision rules are available, 7 33 all are at the derivation stage and await external validation.
Most focus on the derivation stage with only a minority progressing to validation and very few undergoing impact analysis.
Results from the rule derivation stage of the task were also analyzed using a 2 × 2 factorial design with rule complexity and rule familiarity as factors.
Similar(51)
We observed induction of differentiation by ROCKi in cells of mouse, rat, and human origin, of differing derivation and stage of maturation, thus validating the relevance of the observations across species.
This was a prospective survey administered in two stages: derivation and refinement of the original rules (first stage) and validation of the refined rules (second stage).
Two preceding sections describe a two-step procedure of in vitro hepatocyte derivation via the stage of induced pluripotency.
The control tissue cohort was split to provide control lung expression profiles for both derivation and validation stages.
Experiment 2 was designed to replicate the functional dissociations observed in experiment 1, while investigating whether regional activations observed during increased rule complexity were specific to the rule derivation or application stages of the reasoning process.
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