Sentence examples for derivation of exposure from inspiring English sources

However, recent evidence suggests that toxicology outcomes used in derivation of exposure limits may not represent the most sensitive endpoints.

The conference ended with a round table discussion on implications of the new findings for the scientific derivation of exposure limits.

However, because of individual and life-stage variability in the effectiveness of these homeostatic controls and in thyroid reserve capacities, potential sensitive subgroups must be considered in the derivation of exposure limits for perchlorate (Ginsberg et al. 2007; MA DEP 2006; Savin et al. 2003; Scinicariello et al. 2005; van den Hove et al. 1999; Zoeller 2003).

The Building Resilience Against Climate Effects (BRACE) framework developed by the Centers for Disease Control for public health agencies to prepare for climate change suggest derivation of exposure-outcome relationships to estimate the disease burden for climate-sensitive environmental exposures [ 43].

There is a need of guidance on how local irritancy data should be incorporated into risk assessment procedures, particularly with respect to the derivation of occupational exposure limits (OELs).

We excluded the study by Mohner et al. (2013) because the mean cumulative EC exposure in the reference exposure category (624 μg/m-years) was higher than almost all of the nonreference exposure categories of the other studies, the cohort included only 68 lung cancer deaths, and the derivation of the EC exposure metric was not described in detail.

As discussed below, the data documenting the lack of chronic formaldehyde-induced nasal histopathology at concentrations of 1 ppm or less challenge the derivation of Chronic Reference Exposure levels (RELs) or other regulatory guidance levels based on reports of nasal lesions (i.e., rhinitis, squamous metaplasia or dysplasia) in occupationally exposed workers.

Our findings contradict the widely held view (COT 2002; VKM 2008) that chemical mixtures exhibiting varied modes of action are without combination effects at levels near supposed dose thresholds, used in regulatory toxicology as points of departure for the derivation of tolerable human exposures.

Here we further provide a detailed derivation of the maximum permissible exposure (MPE) when PAOM works at the 1064-nm illumination.

The specific settings we used in the derivation of the SNCD-based exposure guideline were selected primarily as a result of such considerations; that is, using these settings, the SNCD concept can be compared to more standard BMD and NOAEL approaches at the level of the human exposure guideline in a calibrated manner, providing a starting point for further discussion.

Although a linear extrapolation model and a target risk of 1/1,000 were used for derivation of the SNCD-based human exposure guideline, other models for low-dose extrapolation, and target risks relevant from a public health point of view, may be considered as the SNCD concept is further developed.