The following parameters were evaluated for invasive lesions: depth of invasion (stage), degree of differentiation (grade), lymph-vascular infiltration, submucosal invasive depth (distance from the bottom of muscularis mucosa to the base of cancer nests) [ 4].
The great depth of the stage at Wuppertal enables such ambitious visions.
Cytoplasmic FOXF1 protein expression in tumor epithelial cells positively correlated with the histologic grade, depth of invasion, stage and lymphatic metastasis of colorectal adenocarcinomas (p < 0.05).
Notably, αGlcNAc expression was inversely correlated with depth of invasion, stage, and venous invasion.
Loss of αGlcNAc was significantly correlated with depth of invasion, stage, and venous invasion by differentiated-type adenocarcinoma.
The neoplasm involved the entire glans and distal part of the urethra, with up to 1.5 cm depth of invasion (Stage T3).
The prognostic evaluation and treatment of vulvar carcinoma patients have been primarily guided by the lymph node status, the size of the tumor, depth of invasion, stage of the disease and grades [ 5- 7].
In the present study, we showed that αGlcNAc loss in MUC6-positive gastric carcinoma cells was significantly correlated with depth of invasion, stage, and venous invasion in differentiated-type but not undifferentiated-type adenocarcinoma.
We found no significant relationship between the expression of Glut-1 in tumours and the accepted clinical prognostic factors of tumour stage, depth of invasion (T stage), nodal status, tumour size and grade of differentiation.
Clinicopathological characteristics in our study included age, gender, tumor size, degree of histological differentiation (well/moderate/poor, WHO), depth of infiltration, staging, and status of lymph nodes and liver metastases.
