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"We kind of know how to help".
We sort of knew how she felt.
It's nigh impossible for any one person to have the breadth and depth of experience to know how all the UI, networking, storage, scheduling and security systems work on their own, let alone in conjunction with one another.
Iona has proved herself indispensable to the business and has an unparalleled depth of know-how, customer understanding and drive – particularly impressive after only two years into her first job.
We were interested to know how depth of coverage affects the sensitivity of INDEL detection in WGS data.
It helps also to measure the motor's depth, so you know how far into the book you should cut.
You don't actually have to know how any of these work in depth, as you won't need to interface with them directly.
It is useful to know how the temperature of maximum density changes with depth (e.g., from 3.94 °C at the surface to 3.39 °C at 500 metres depth [38.10 °F at 1,500 feet]).
In fact, in order to calculate the absorption loss, one needs to know how many skin depths the shield material represents at the frequencies of concern.
It is impossible to know the depth of one woman's impact on the school, just as it is impossible to know how the school might have shaped her life or judicial thinking.
None of us know how to play.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com