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Water responding (data not shown) was unaffected by the deprivation period in any of the three deprived groups, and remained at approximately 15±4 responses/session.
The fitted deprivation gap in survival between the most affluent and most deprived groups was estimated using variance-weighted linear regression.
As a result, the deprivation gap in survival between the most affluent and the most deprived groups increased steadily.
The deprivation gap in survival between the most affluent and the most deprived groups is approximately 4%.
Post hoc comparisons revealed that rats given repeated deprivations had a two-fold higher breakpoints values (FR values 30 32 for deprived groups vs 15 for the nondeprived group) and four-fold higher ETOH lever responses than the nondeprived group (700 900 responses for deprived groups vs 200 responses for nondeprived group).
*p<0.05 (values for all three deprived groups greater than the nondeprived group).
As is the case with other studies, the benefit is seen most clearly among low income and socially deprived groups.
Following this initial period, the deprived groups were given 15% ETOH again in the operant chambers for a 2-week period, following which they were deprived again for 2 weeks (all three deprived groups).
In areas with poor air quality, 32% of people living there were from the most deprived groups, versus 7% from the least deprived.
Breakpoint values for responding on the ETOH lever for all three deprived groups were two-fold higher than the value for the nondeprived group.
Following the fourth deprivation, the rats underwent a progressive ratio test to determine the breakpoints (FR values) for the nondeprived and the deprived groups.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com