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As tumors depend on the generation of new vasculature to proliferate, targeting neovascular cells is another approach to inhibit tumor growth that might "starve" tumors as cancer cells are deprived of blood flow.
The eye catches just the surface of things -- the drought-deprived flow in the creek bottoms, the long rows of round bales stacked against the prevailing winds, the superficial differences that separate wild land from rangeland from hayground.
NCT01341236 Intra-uterine growth restriction (IUGR) caused by placental insufficiency is characterized by blood flow redistribution to the vital organs (brain, myocardium, and adrenal glands), while other organs, including the gastrointestinal tract, are deprived from sufficient blood flow.
AKI can also develop after major surgery, such as some kinds of heart surgery, because the kidneys can be deprived of normal blood flow during the procedure.
If a nerve fibre is severed, the length of axon farthest from the cell body, or soma, will be deprived of the axonal flow of metabolites and will begin to deteriorate.
Brain injury causes swelling and impaired blood flow, depriving the brain of oxygen.
The loss of blood flow deprives brain cells of oxygen, but cooling can delay the process of cell death.
The canals are bone dry because upstream groundwater pumping in the Roswell area has deprived the Pecos River of its flow.
Most of these features are unfair and inefficient from the perspective of low priority (non-real time) traffic flows as they tend to starve the non-real time flows depriving them of appropriate channel access, hence throughput.
This might sound uncontroversial, but one of the worst problems in our deprived areas nowadays is the ceaseless flow of new schemes and initiatives.
Patients with ischemic stroke are usually treated with tissue plasminogen activator (tPA) to increase blood flow to the oxygen deprived brain region.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com