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Prior to screening, the only significant difference in case-mix between specialists and nonspecialists was the distribution by socioeconomic status (specialists treating more women in the affluent and deprived categories), although the trend across the deprivation categories was not significant.
The 'deprivation gap' in relative survival in the trial was estimated with variance-weighted linear regression as the fitted difference between the 'most affluent' and 'most deprived' categories (Grizzle et al, 1969), and compared with the deprivation gap for the general population of England and Wales (Coleman et al, 2004).
The deprivation 'gap' in survival between the most affluent and the most deprived categories was estimated using least-squares linear regression.
After removing from the research households in the "most deprived" categories, Rost's team focused on those working but are nevertheless suffering high levels of financial stress.
As expected, the prevalence of smoking in the most deprived categories was greater than in the least deprived categories, with both the self reported and cotinine validated estimates.
Survival rose slightly more for women in the deprived categories than for the more affluent groups.
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There were differences between men and women in their marital status (88% of men vs. 60% of women were currently married), education (more men than women in vocational category), material deprivation (more women than men were in the most deprived category) and history of unemployment (slightly more women were in categories with longer history of unemployment).
In terms of deprivation scores, one-fifth of the total study sample were from the most deprived category (n=121) and one-quarter (n=152) from the least deprived category.
Response rates differed according to deprivation status (table 1) with a response rate of 71.4% in the least deprived category compared with 57.1% in the most deprived category (p<0.001).
More than half of the patients belonged to the most deprived category.
Poorer outcomes in FACT-B items were associated with being in the most deprived category.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com