However, our results suggest that fatigue may play less of a role in sleep than previously thought, and that other factors, such as depression, leg cramps, and pain management, should be addressed by physicians and patients in discussions related to sleep difficulties.
However, it does have its own unique side effects, including:[6] Nausea/indigestion Trouble sleeping Depression Leg or arm pain.
The diseased ducks showed depression and leg weakness.
His past medical history was significant for type 2 diabetes mellitus, hypertension, hyperlipidemia, depression, restless leg syndrome, cluster headaches, benign prostatic hypertrophy and kidney stones.
In a regression model variables statistically significantly associated with sleep problems included depression, nighttime leg cramps, younger age, pain, female sex, fatigue, shorter duration of MS, and nocturia.
Our results suggest that there are a number of factors (depression, pain, leg cramps, fatigue, and nocturia) that may contribute to sleep problems in MS that are potentially modifiable, and when treated could improve sleep in MS patients.
Additional information on sleep problems and sleep disturbances scores can be found in Table 2. Variables statistically significantly associated with sleep problems included depression, nighttime leg cramps, younger age, pain, female sex, fatigue, shorter duration of MS, and nocturia (Table 3).
Self-reported comorbidities were generally more common in MRC 3, 4 and 5 patients compared with MRC 1 and 2 patients, and included hypertension (37%), anxiety (36%), depression (34%), leg muscle weakness (30%), heartburn (29%), arthritis (28%), hyperlipidaemia/high cholesterol (22%), sleep apnoea (23%) and diabetes (20%).
Borderline cases chronic fatigue syndrome, major depression, restless-legs syndrome are vexing precisely because they lack those indicators.
Borderline cases — chronic fatigue syndrome, major depression, restless-legs syndrome — are vexing precisely because they lack those indicators.
WOMAC function scores at each visit were compared by analysis of covariance adjusting for age, sex, body mass index, race, site, depression, comorbidity, painful leg joints and knees affected.
