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Chemo-radiotherapy specifically degrades muscle mass, and depresses the function of mitochondria, the tiny structures that act as the boiler room of the cell, generating energy.
Anything that depresses the function of these blood cells can make one vulnerable to infections like the common cold or other viral infections of the respiratory tract.
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Leukaemic plasma depressed the function of control granulocytes; the possible role of a plasma "factor" is discussed.
Halothane has been demonstrated to depress the function of a wide variety of both invertebrate and mammalian K+ channels [ 25], including the KCa++ channel in rodents [ 26], and in canine cerebral and coronary vascular smooth muscle [ 27].
Barbiturates act by depressing the central nervous system, particularly on certain portions of the brain, though they tend to depress the functioning of all the body's tissues.
It is generally believed that stresses depress the functions of the immune system.
In other cases, parasites stimulate rather than depress the functions of regulatory T cells decreasing T-mediated host damages.
The down-regulation of genes related to immunity and defence response may suggest that stressors depress the functions of some immune-related genes in the intestine.
It "depresses" or inhibits the function of neurons by reducing their ability to transmit or "fire" electrical impulses.
The function of wtp53 is depressed by mp53 in a way that mp53 forms heterogeneous tetramer with wtp53.
Patch-clamp and pharmacological studies on cell bodies of sensory neurons showed that the function of SERCA pumps was depressed in diabetic cultures, as was expression of SERCA2a protein (confirmed in a previous in vivo study with intact lumbar DRG; Verkhratsky and Fernyhough, 2008), and could be responsible for impaired loading of Ca2+ into the ER.
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