Sentence examples for depletion of bone from inspiring English sources

Cytotoxic drugs cause a depletion of bone marrow cells.

GIOP patients are at very high risk of fractures through the depletion of bone mass [ 10, 11].

We next investigated potential mechanisms by which Rps27l disruption induces apoptosis and causes the loss of HSPCs and depletion of bone marrow.

The slow release of lead suggests depletion of bone stores acquired during pregnancy, possibly due to pica behavior of the mother during pregnancy.

AVL is a systemic infection affecting lymphoid organs; it is associated with parasite antigens driving an impaired T-cell response leading to a depletion of bone marrow as well as systemic CD4+ and CD8+ T lymphocytes.

Additionally, CD4 T cell depletion of bone marrow caused by both HIV infection [ 33] and AVL [ 9, 11] was already demonstrated and may lead to deficiencies in the input of new lymphocytes into the periphery.

The model of chemotherapy is based on transient cell depletions of bone marrow compartments in dependence on drugs and drug doses.

In this study, we determined the consequences of Hdac3 depletion on bone formation by crossing mice with loxP sites flanking exon 7 of Hdac3 [11] to mice wherein Cre recombinase is expressed from the endogenous osterix (Osx) promoter [30].

In this study we focused on the postnatal consequences of Hdac3 depletion on bone structural and cellular properties.

The negative effect of estrogen depletion on bone appears to be associated with all AIs [ 17, 33].

In the absence of structural bone formation, continued osteoclastic resorption of structural bone will result in a depletion of structural bone, ultimately leading to osteoporosis.