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This represents an average depletion of approximately 83% of total protein per sample.
RNA-seq confirmed CYP2S1 depletion of approximately 3-fold in these samples.
This study showed that a depletion of approximately 90% of the Tregs in the tumour microenvironment led to normalization of the tumour vasculature and T cell infiltration which resulted in tumour rejection.
Moreover, we observed a depletion of approximately 18% marked gene families, on the contrary to what one would expect if comparing with genome average (supplementary fig. S1 C, Supplementary Material online).
Treatment of mice with anti-Ly-6C/Ly-6G antibodies (clone RB6-8C5) is a well-established method that results in the depletion of approximately 97% of circulating neutrophils [ 20, 53, 54].
To test this possibility, IL-6RαT-KO mice were either left untreated or injected with a monoclonal antibody (mAb) against CD25, which resulted in the depletion of approximately 80% of Foxp3+ Tregs prior to immunization with OVA and LPS in IFA.
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Interestingly, Gu et al. (2003) reported a high depletion of Dicamba concentration (approximately 95%% after 28 days), which is contrary to the obtained results (primary degradation of Dicamba was <70 % for all studied microbiota samples).
TRF2 depletion triggered fusion frequencies of approximately 17.6%, whilst concomitant Brca1 deletion caused a reduction to 8.2% (Fig 2B), in the same range as CtIP depletion (6.6%).
Theoretical model scenarios with scaled abstraction rates show that lens contraction caused by pumping is a nearly linear function of the total pumped volume, whereby the abstraction rate and the timing of depletion are approximately inversely proportional.
Most had red blood cell folate concentrations indicative of depletion whilst approximately one-third were deficient.
RIT causes a transient depletion of B cells for approximately six to nine months.
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