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The authority has failed to promote sergeants to lieutenant, but has continued to promote lieutenants to captain, thereby causing a further depletion in the number of available lieutenants and increasing the need for overtime.
[7] In this context, depletion in the number or function of Treg appears to contribute to HIV-1 progression.
This protocol results in a > 4‐fold depletion in the number of DAn (See Materials and Methods and (Sanchez‐Danes et al, 2012a)).
HIV is a disease that is accompanied by a profound depletion in the number of CD4+ T cells and can be transmitted by blood or other body fluids [ 2].
In vivo, depletion in the number of germ cells observed in mouse fetal gonads after Cd exposure (Tam and Liu 1985) leads to a defect in germ cell maturation in both sexes and subfertility in males.
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This is in contrast to the previously described ultrastructure of the islets in R6/2 mice [25], in which there was a depletion in the numbers of β-granules in the β-cells and a reduction in the numbers of β-cells with a resultant reduction in the size of the islets, a result that we confirmed in this study (Figure 3E).
If, however, a diploid strain (labeled in red) has experienced a depletion in the copy number so that it now has only two copies of the gene, the R/G hybridization ratio will be 0.5 because the copy number relative to the haploid state has been lowered.
Because so many contiguous genes are involved in this block of genes, and because almost all of the genes exhibit a similar direction and magnitude of deviation, we believe that this region has been lost from either one or both copies of chromosome 7 in the (presumably diploid) Lalvin isolate, yielding a net depletion in the copy numbers of these genes relative to the reference strain.
This program enabled the determination of the most highly represented GO categories in response to GR depletion, and the number of genes in each set (up and downregulated) belonging to those categories.
With a much greater set of reads mapping to the intergenic and intronic regions in rRNA depletion protocols, the number of additional transcripts detected with the new protocols may be expected to be greater than our conservative estimation here.
However, peritoneal macrophages from Adrp knockout mice accumulate fewer LDs upon cholesterol loading, and in atherosclerosis-prone apoE knockout mice, ADRP depletion decreases the number of LDs in foam cells, yet protects mice from atherosclerosis (Paul et al, 2008).
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