Sentence examples for depletion generates from inspiring English sources

IL-2, in association with Treg depletion, generates "hyperactivated" natural killer (NK) cells, possessing antitumor activity and secreting factors that facilitate virus spread/replication throughout the tumor by disrupting the tumor architecture.

Its overexpression interferes with protein synthesis and suppresses proliferation [26], while its depletion generates supernumerary centrosomes, multinucleated cells, and multipolar spindle formation in NIH3T3 cells [27].

Thus partial patch depletion generates novel niche opportunities, in a process related to niche construction [ 30, 31] or niche creation [ 32].

Another Rab described in this context is Rab6c, which is localized to the centrosome and whose overexpression results in G1-phase arrest and whose depletion generates tetraploid cells [ 49].

Kosch et al. ([2007b]) showed that the pump beam forms a large-scale density depletion generating a reflective concave HF mirror which focuses the pump wave energy into a small region when pumping in the magnetic zenith.

Cells infected with shRNAs that resulted in a partial E-cadherin depletion generated polyclonal populations that either lost E-cadherin suppression over time (shEcad#24), or exhibited a partial reduction of E-cadherin levels for the duration of these studies (shEcad#23) (Figure 6A, B).

Sabnis and coworkers [ 8] now confirm that HER2 and PI3K/AKT signalling (but not MAPK) is upregulated and growth contributory in a new model (UMB-1Ca) of acquired resistance to oestrogen depletion generated from ER-positive aromatase-transfected MCF-7Ca cells in vitro.

Unlike NMY-2 depletion, which generates 100% dead embryos, the lethality of mel-11 mutants is rescued by wild-type sperm so the chromosome constitution of progeny from a mel-11 mother can be scored by phenotype.

To rule out effects of c-Kit blockade on responses to physiological SCF sources, and to rule out antibody mediated depletion, we generated a SCF null 4T1 cell line (supplemental Fig. 6c, d).

This component can measure real-time energy consumption, emulate battery depletion, and generate artificial sensor data, hence emulating real-world application scenarios.

To assess the long-term effect of prohibitin depletion, we generated HeLa cell lines with inducible shRNA expression.