In addition, ATP-depletion expected to occur during the demise of the larvae would likely interfere with the ATP-dependent processes of 26S proteasome assembly and normal protein turnover.
As reported previously from transient siRNA-mediated depletion [15], we expected depletion of CAML to convert these cells to the permissive, Vpu-unresponsive phenotype.
Co-depletion of hBora with Plk1 suppressed the accumulation of hBora that normally results from Plk1 depletion, as expected (Fig. 6a).
Further, we found that TRIM24 protein, which was dramatically increased upon SPOP depletion as expected, was no longer dependent on TRIM28 expression in the absence of SPOP (Supplementary Fig. 3a).
Both disorganized metaphase (Fig. 1B, D) and centromere stretching (detected with CREST antibody; staining includes the inner kinetochore and chromatin connecting the two sisters) (Fig. 1E, F) were associated with SMC2 depletion, as expected.
B cell depletion is expected to have multiple direct and indirect effects on the autoimmune response.
A relatively high possibility of nutrient depletion is expected for SWCNT and graphene, which have larger surface areas and higher adsorption capacities for organic molecules.
Changes in serum TSH and TT4 after only 1 day of ClO4− treatment were surprising because thyroidal iodide depletion was expected to be minimal over this time period, although 26 96% inhibition of NIS thyroidal iodide uptake was predicted by the model, which is in close agreement with Yu et al. (2002).
As expected, depletion of CD8+ cells, or depletion of CD4+ in combination with CD8+ cells, almost completely abolished the IFNγ response (p<0.01 in both cases) (Figure 2).
The K depletion questions whether K substitution is in demand in these patients or whether the K depletion can be expected to resolve following a normalisation in Mg stores.
