"Having trained a bunch of bees, we then tested to see if they would respond in the same way to the mixture that was depleted by exposure to NOx [the reactive chemical in diesel exhaust]," said Dr Newman.
Mcl-1 levels in Arf −/− Eμ -Myc/Mcl-1/Bcl-2 cells are significantly depleted upon exposure of cells to Hipp.
O-methylguanine-DNA methyltransferase is depleted after exposure to alkylating agents, as the protein is consumed in repairing DNA damage.
Military Health Study and Kansas II evaluated depleted uranium exposure using questions regarding contact with destroyed enemy vehicles (or inhalation of smoke from vehicles) that may have been struck with artillery rounds containing depleted uranium [ 14], and exposure to the Camp Doha fire.
None of the physicians reported seeing patients with deployment-related amputations or prosthetic devices, sexual trauma, acinetobacter or leishmaniasis, vision loss, or depleted uranium exposure.
[ACh-e]+ was depleted following exposure to 2 μg/L (1.80-fold, significant by Tukey's post hoc) and 200 μg/L fenitrothion (1.36-fold) compared to the SC group, confirming disruption at the target site (ANOVA, p = 0.009).
Recent investigations clearly show that the cellular ascorbate is greatly depleted by exposure to Ni II) compounds, which results in the inhibition of prolyl hydroxylase activity and activation of HIF-1α and expression of hypoxia-inducible genes.
GSH levels were increased by acute MeHg treatment and depleted with chronic exposure.
In addition, MG-treated cells could prevent intracellular glutathione (GSH) from being depleted following an exposure of H2O2 (8.0 mM) for a 3 h period.
The microarray-based classification of Δtag and ΔdinG cells as depleted after MMS exposure, contrary to plate-based methods, led to the discovery that Δtag and ΔdinG cells show a filamentation phenotype after MMS exposure, thus accounting for the discrepancy.
