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Presence of FRF in the medium along with STZ has depicted a dose dependent reversal of all the cytotoxic manifestations, with the highest dose of 250 μg/mL normalizing most of the measured parameters except for peroxynitrite and NO formation and total cell viability.
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The FRF fraction depicted a dose-dependent 5-15 fold increase in glucose uptake even in the absence of insulin.
FRF depicted a dose-dependent reversal of all the cytotoxic manifestations except peroxynitrite and NO formation when subjected in-vitro along with STZ.
Results shown in Figure 4A depict a dose-dependent decrease in the level of HPV18 transcripts in cells treated with crude extracts and fraction F4.
Figure 4 shows the percentage inhibition of oxidative burst of the Phyllanthus species and the pure compounds on PMA induced leukocytes, depicting a dose-dependent relationship.
Under both basal (4.5 mM) and higher (16.7 mM) glucose ambient concentrations, the FRF fraction depicted a dose- dependent increment in insulin secretion with the highest dose showing almost doubled insulin secretion.
Figure 3 depicts the effects of a dose dependent reduction in TNFα and IL-6 release from monocytes which have been co-cultured with ACV, together with either C. albicans, E-coli or S. aureus for 24 h.
Addition of PNA ftsZ suppressed bacterial growth in a dose dependent manner (Fig. 5bb).
Addition of Pb2+ increased annexin-binding to the cells in a dose dependent manner (Fig. 2).
Fig. 3 a Dose dependent DPPH radical scavenging activity.
MEIL displayed anti-inflammatory activity in a dose dependent manner.
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