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The formation and maintenance of these tumors depends upon the expression of Wnt1 ligand; thus, in mice that conditionally express Wnt1, tumors regress upon withdrawal of Wnt1 ligand expression [13].
Since the detection of gene transcripts by transcriptome sequencing depends upon the expression of those transcripts, those transcripts that are only expressed at certain life-stages will be missed.
Positive regulation of CDK activity depends upon the expression of small polypeptide co-enzymes called cyclins [25].
This result suggested that the growth inhibitory effect of the CPP in cancer cells depends upon the expression of YB-1.
Earlier we and others have shown that inability of B6 mice to control progression of M. avium-triggered disease largely depends upon the expression of a non-functional Nramp1s allele [15], [19].
The efficacy of 5-fluorouracil (5FU -based therapy, which remains the cornerstone of gastrointestinal cancer treatment, depends upon the expression of enzymes involved in pyrimidine metabolism, including thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), thymidine phosphorylase (TP), and orotate phosphoribosyltransferase (OPRT).
Similar(52)
Overall, these results suggest that ZD6474 can inhibit EGFR-dependent tumour growth, and also that the magnitude of inhibition may depend upon the expression of mutant EGFR.
The number of cycles used was varied depending upon the expression level of the gene under study.
SIF associates a probability of failure with different biological functions and models stochasticity in these functions depending upon the expression of the input nodes.
In all three cell lines, p21 promoter activity depended upon the expression of vimentin as demonstrated using a vimentin siRNAs pool in comparison with control siRNAs.
SIF associates a probability of failure with different biological functions and models stochasticity in these functions depending upon the expression of the input nodes (similar to concentration of reactant species in CME).
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CEO of Professional Science Editing for Scientists @ prosciediting.com