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Rather, addition of the ONO-1301SR placementherapypy to the cell transplantation therapy may prolong the regenerative effects for the cardiac tissue, depending upon expression of IP receptor and subsequent intracellular signalling in the transplanted cells.
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Understanding the biologic functions of chemokines has largely depended upon expression of these recombinant molecules in E. coli.
We find that GBS induces cardiomyocyte dysfunction and promotes cardiomyocyte death in a fashion that depends upon expression of its β-h/c toxin.
We characterized a gene expression phenotype associated with high-scoring cell populations, with the expectation that the capacity of cells to home to liver tissue and attach to endothelial substrates would depend upon expression of receptors or key cellular components.
The ability of a cell population to infiltrate hepatic tissue may depend upon expression of key receptors that facilitate homing to liver, attachment to endothelial surface, or transendothelial migration into the tissue [19].
The number of cycles used was varied depending upon the expression level of the gene under study.
The above two studies suggest that miR-133 has two potential roles in the diabetic heart, depending upon whether expression is increased or decreased.
SIF associates a probability of failure with different biological functions and models stochasticity in these functions depending upon the expression of the input nodes.
SIF associates a probability of failure with different biological functions and models stochasticity in these functions depending upon the expression of the input nodes (similar to concentration of reactant species in CME).
Thus, we observed that the mechanisms driving celecoxib-induced growth inhibition are very diverse in the two cells lines, depending upon COX-2 expression levels, invasive properties, and dependence on PGE2.
Notably, VEGF expression was shown to depend upon ATF4 expression under certain conditions [ 50] and we hypothesize that such a regulatory circuit exists in these cells, whereby ErbB2-augmented GF signalling would promote VEGF expression through up-regulation of ATF4.
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