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The CDS-AE proportion of the entire CDS involved in metabolic pathways was about 75%, but the proportions varied depending on the pathways (Table 8).
In general, attendees agreed that intravenous data can be important in PBPK model development (depending on the pathways).
Defects in DNA repair pathways confer enhanced sensitivity to specific DNA damaging agents depending on the pathways affected.
Similar(57)
We do not propose a single drawing but rather several alternative ways of presenting metabolism depending on the pathway on which one wishes to focus.
This was driven by different factors, depending on the pathway in which the drug was evaluated.
LC WTW (well-to-wheel) GHG emissions range from 106.8 to 116 g-CO2equivalent/MJ of gasoline, 100.5 to 115.2 g-CO2equivalent/MJ of diesel, and 96.4 to 109.2 g-CO2equivalent/MJ of jet fuel, depending on the pathway.
Recent understanding of the impact of cytokine signaling pathways on HSC homeostasis is beginning to show positive and negative effects depending on the pathway and degree of activation.
It is well known that ligand-induced activity of signaling proteins in a MAPK cascade can be promoted in an ultrasensitive manner depending on the pathway structure and kinetic parameters [24], [25].
Depending on the pathway, different features are discussed [ 27– 29].
Depending on the pathway, the activity of Prp43 is modulated by different G-patch proteins.
The mechanism shown in Figure 6A has a variable stoichiometry, depending on the pathway.
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CEO of Professional Science Editing for Scientists @ prosciediting.com