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Today, depending on the mutations found in individual tumors, there are several unique drugs available to treat metastatic NSCLC.
We also noted that the extent to which Dsh was phosphorylated (visualized by a change in electrophoretic mobility, Fig. 4) was different depending on the mutations that were made.
As soon as clones reach the size Lc, they start to collide with neighboring clones, which may have higher or lower fitness depending on the mutations they have accumulated in the past.
Fc domains exhibiting decreased fucosylation, by comparison, enhance binding only to CD16A [ 39, 41], and other mutations reported to increase binding to activating receptors also demonstrate increased binding to CD32B but to different extents, depending on the mutations [ 37, 38].
AGXT mutations result in severe reductions of AGT enzymatic activity in the peroxisome, with a relatively wide range of residual activity, depending on the mutations present in both alleles [ 35].
Although our recommendations are pertinent to classical CF risk rather than the milder phenotypes discussed, there are some mutations that may be associated with mild or severe forms of CF depending on the mutations with which they are paired, thereby complicating the process of selecting mutation panels.
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The hub activity exhibits an abrupt change depending on the mutation frequency.
It is found that depending on the mutation rates, different designs are evolutionarily advantageous.
Different treatments may work in different molecular subsets of cancer, depending on the mutation.
Depending on the mutation rate, the species-area relationship displays either two-phase or a triphasic scenario.
Depending on the mutation, older antiviral drugs like rimantidine may be useful, but so much resistance to them developed in seasonal flu that they were largely abandoned a few years ago.
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CEO of Professional Science Editing for Scientists @ prosciediting.com