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Depending on the dosing conditions, three different ordered overlayer structures were formed, only one of which has been previously reported.
It will be interesting to determine the total length of time that siRNA could be maintained in the nasal cavity, middle ear, and ET, as it has been reported that knock down of a target can last days to weeks depending on the dosing regimen [38].
Response rates varied depending on the dosing schedule utilized in these trials.
For these agents, incidence of nephrotoxicity was described in 10 to 20% of patients depending on the dosing regimen [ 12].
Inhibitors that reduce 4βHC by 20% would be expected to increase MDZ AUC by 20- to 26-fold, depending on the dosing regimen.
In mice, weight evolution can either be repressed or enhanced by antibiotics, depending on the dosing, treatment duration and mouse strain used.
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Depending on the dose, sulforaphane reduced burns up to 83percentt compared with similarly exposed bare skin.
Depending on the dose, "we decreased their body weight by almost half -- that's enormous," Dr. Rupnick said.
Radiation can have various health effects, depending on the dose and form.
It'sis a neurotoxin that can affect not just insects, but birds, other animals, even the winemakers, depending on the doses used.
Because it is a single injection, its duration is limited, generally lasting about two hours, depending on the dose.
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