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Additionally, the TGF-β dependent transcriptional patterns are strongly depending on the differentiation status of the hepatocyte.
Moreover, proteoglycan synthesis is also differentially regulated by TGFβ in rabbit and bovine chondrocytes depending on the differentiation stage of the chondrocytes [ 54, 55].
Recent studies affirmed that bFGF has both mitogentic affects and reversibly inhibits differentiation depending on the differentiation state of the treated cells [72].
These results suggest that the TRPM8 expression depending on the differentiation status.
However, all groups varied both quantitatively and qualitatively depending on the differentiation stage.
In B cells, ligation of CD38 by agonistic antibodies triggers different in vitro responses depending on the differentiation stage of the cells.
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Overall, the therapeutic implications of these results are that the effectiveness of ALA-dependent PDT depends on the differentiation status of the cell and that this may enable selective targeting of several tissue types.
In some experiments, conducted to demonstrate that leptin/IL-1 synergism does not appear to depend on the differentiation state of the chondrocytes, chondrogenic ATDC5 cells were differentiated into mature and hypertrophic chondrocytes, as described by Thomas and coworkers [ 19].
The obtained results indicate that the performance of reference genes depends on the differentiation protocol and on the analysis time, thus providing valuable information for the design of RT-PCR experiments.
Similarities and differences between maize and Arabidopsis are analyzed and discussed, also considering that their different plant architecture depends on the differentiation of structures whose development is controlled by auxins.
Splicing patterns of CEACAM1 did not depend on the differentiation grade of tumor sample.
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