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The ART superfamily can be divided into two major clades depending on the conservation pattern of the three key active site residues associated with the three conserved motifs, respectively from the N-terminus, central region and C-terminus of the domain.
Addressing all these goals would need an increase in area between 7 and 46%, depending on the conservation target used and strength of connectivity required.
Therefore, the rareness of invariant sequences differs depending on the conservation background in each alignment.
Depending on the conservation of the underlying pathways, there are two main approaches to studying them in yeast.
The information on the program used to generate the consensus is provided in the header of Additional File 1 (the % of consensus was chosen ad hoc depending on the conservation with a family).
While the feature value is 1 for the WDS kernel if the k-mer is present at a certain position, for the WDSC kernel the feature value is γ d, i, x, i.e. it is computed depending on the conservation of the k-mer at this position.
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The results of statistical analysis of simulation data obtained from long time integrations of geophysical fluid models greatly depend on the conservation properties of the numerical discretization used.
We show that features which depend on the conservation of mass, momentum or energy, or which involve a balance of forces, are generally reproduced well.
The universality of the primers for EPIC PCR depends on the conservation of exonic sequences, and the efficiency of PCR amplification may be primarily affected by gene copy number, including pseudogenes.
The universal specificity of primers may depend on the conservation of exon sequences whereas the efficiency of isolating a single copy of the target nuclear genome may be a function of the number of duplicate gene copies, paralogs, and/or pseudogenes.
The biological significance of the test is determined by the epitope specificity of the mAb used in the EB-ELISA, and its broad applicability depends on the conservation of the epitope among H5N1 viruses.
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