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DNA exerts complex effects on the immune system, depending on its sequence.
There is significant fluctuation of the charge distribution in the backbone carbonyl group depending on its sequence location because of its different electrostatic environment as a result of specific hydrogen-bonding interactions with the solvent and polarization by nearby residues.
While the proviral DNA, depending on its sequence composition, may attract host proteins including transcription factors and chromatin remodelling proteins already prior to integration, the retroviral protein components of the PIC can act as additional attractors of host proteins (Fig 1).
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The frequency of incorporating mutations at a given end may depend on its sequence.
Of course, not all sequences are equivalent in the real world, and whether a molecule can function as a catalyst depends on its sequence and structure.
Our study supports the notion that the epigenetic fate of the retrotransposed DNA depends on its sequence and selective forces at the integration site.
However, analysis of data from metabolic labeling experiments can be complicated because the spacing between labeled and unlabeled forms of each peptide depends on its sequence, and is thus variable from analyte to analyte.
As the number of sequences is an intrinsic property of the classification, and depends on the Hamming distance with respect to the master sequence, in order to change the robustness of each Hamming class, we assume that the quality factor per digit of each species, qi, depends on its sequence, as previously done in [ 48].
The first classifier is based on the distance measures and predicts the tropism of a sequence depending on its average distance from all NSI/CCR5-tropic sequences in the training dataset.
Moreover, it allows to effectively target any quality defined in terms of PSNR or MSE while a fixed QP solution may result in rather different average qualities along a video sequence depending on its characteristics.
The structure of the genetic code imposes constraints on the evolutionary variability of a nucleotide in a gene sequence, depending on its codon position.
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