Finally, the decision on the exact number of drugs and length of therapy also depend on extent and site of disease, penetration of the chosen drugs and treatment response.
In response to DNA damage, p53 transactivates a range of genes to induce cell cycle arrest, DNA repair, senescence and apoptosis, depending on the extent and types of DNA damage (Sionov et al., 1999; Vousden et al., 2002).
If reversible hypoperfusion is demonstrated on SPECT MPI indicating ischemia, these patients are often referred for invasive coronary angiography depending on the extent and severity of the defect and symptomatic status.
Examinations took between 50 and 60 min depending on disease extent and patient mobility.
Depending on the extent and direction of bias in primary studies, the AITC and MTC estimates could be more or less biased than the DTC estimates.
Depending on the extent and direction of biases in different sets of studies, ITC and MTC methods may be more or less biased than direct treatment comparisons (DTC).
Depending on the extent and direction of biases in different sets of studies, indirect and mixed treatment comparisons may be more or less biased than the direct comparisons.
Moreover, the potential for contact between agricultural and noncrop communities will itself vary across landscapes depending on the extent and configuration of cropping systems.
Although the core processes of wound repair are common to all tissues, there can be substantial differences depending on the extent and nature of the insult, as well as the affected tissues and cell types.
The divergence of nucleo-cortical axons in the cortex varied depending on the extent and localization of viral transfection, coarsely following the known cerebellar modules (Apps and Garwicz, 2005; Pijpers et al., 2005; Apps and Hawkes, 2009).
