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Within the group of PK genes, selective pressure on non-synonymous sites varied significantly depending on expression levels and the number of tissues in which genes were expressed.
In order to help selection of a model depending on expression of a specific feature of dystonia, this review is organized by symptoms and current knowledge of pathogenesis of dystonia.
Hence, depending on expression of the flagellin proteins, the species are predicted to have different capacities for motility.
In conclusion, plumbagin induces apoptosis in colonic cancer cells through TNF-α mediated pathway depending on expression of COX-2 expression.
It is possible therefore, that mutant polyglutamine proteins do not necessarily cause a global impairment of the UPS, but rather may affect certain branches of the UPS depending on expression levels, cell type and subcellular localisation.
Thus, several repressor complexes involving FE65 might form (FE65/Teashirt/HDAC, FE65/SET, or possibly FE65/Teashirt/HDAC/SET), depending on expression levels of these proteins, subcellular compartmentalization, and possibly steric considerations.
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DNA damage-induced G2/M arrest depends on expression of p21, an inhibitor of the cyclin-dependent kinase cdc2.
Here we examine whether this degeneration depends on expression of mutant SOD1 in muscle fibers.
Production of proteins as therapeutic agents, research reagents and molecular tools frequently depends on expression in heterologous hosts.
In addition they showed that paraspeckle assembly and function depend on expression of a long nuclear-retained non-coding RNA, NEAT1, which is not detectable in hESCs.
For instance, the efficacy of epidermal growth factor receptor (EGFR) antagonists has been shown to depend on expression of its target -EGFR- in the tumor [3].
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