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Our data provide the first evidence that the components of a functional FcεRI are in vitro expressed by the human intestinal epithelial cells depending on differentiation and, more importantly, in situ in epithelia of patients with colon cancer or gastrointestinal inflammations.
This observation suggests that Kitasatospora incorporates different DAP isomers into the cell wall depending on differentiation stage.
This suggests that the composition of cell wall peptidoglycan would be regulated in Kitasatospora depending on differentiation stages.
In different tumor cell types, depending on differentiation status and environment, CXCR4 and CXCR7 may be expressed uniquely or in combination.
Cardiac sarcoma remains one of the most aggressive primary cardiac tumours, which can arise from different cardiac chambers and demonstrate various features, depending on differentiation and histologic composition.
For Accutase subculture onto Transwells, treatment length varied depending on differentiation state of the cells (20 25 min for cells without RA treatment, 30 45 min for cells with RA treatment, until a singularized cell suspension was formed).
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Partly because, like chocolate bars or deodorant sprays, there are so many TV channels to choose from, and success in a crowded marketplace depends on differentiation.
Osteoclastogenesis depends on differentiation signals from stromal cells and synovial fibroblasts, and is physiologically triggered by RANKL (receptor activator of NF-κB ligand) in the presence of M-CSF and other co-stimulatory factors.
However the important part of the successful therapy depends on differentiation and promoting the survival of implanted cells.
Although beyond the scope of present study, it would be interesting to see if the pathway activated by the MIF/CD74 couple (AMPK vs PI3K pathways) depends on differentiation of the cancer cells.
Recent studies affirmed that bFGF has both mitogentic affects and reversibly inhibits differentiation depending on the differentiation state of the treated cells [72].
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