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Detection of PAPP-A secreted by the cells into their culture media depends, at least in part, on its molecular structure and it is dependent on the specificity of those antibodies recognizing dimeric PAPP-A, which can successfully be used for assaying this CPC-derived protease.
Scheinberg, P. et al. The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor.
Gene expression studies using reverse transcriptase (RT -PCR aRT -PCRly used are powidely, busedhe results obtanded from such studies are depowerfulon the specificity of the assay.
However, efficiency of this method is dependent on the specificity of the primers.
Just as standard PCR, efficiency of real-time PCR is also dependent on the specificity of the primers.
Chemicals utilizing the protein-mediated mechanisms must resemble the native substrates to the extent that is dependent on the specificity of the carrier proteins.
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Although highly sensitive, the quality of the gene expression assessment by the TaqMan-based method is dependent largely on the specificity of the probe to discriminate among highly conserved miRNA target sequences as well as the sensitivity of the assay probes to quantitatively measure the target miRNA over a wide range of expression levels.
This type of toxicity is a direct result of the specific recognition of a target expressed in normal tissues by CAR-T cells, thus its profile is dependent on the antigenic specificity of the engineered T cell and can be predictably seen in a variety of organ systems (Bonifant et al., 2016; Barrett et al., 2015).
The biological outcome of HDAC inhibition is dependent on the HDAC specificity of the compound and the intrinsic operation of the cell-signaling pathways.
The biological outcome of HDAC inhibition is dependent on the HDAC specificity of the compound and intrinsic operation of cell-signaling pathways.
However, our current understanding of CR suggests that problem solving is largely dependent on the amount, specificity and organisation of knowledge possessed by the student.
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