Sentence examples for dependent on the elevated from inspiring English sources

The sporulation phenotype appears to be dependent on the elevated calcium concentration, a so far undefined component present in casein and a low pH.

We find that, despite severe insulin resistance and the absence of Akt signaling, TSC2-deficient mouse embryo fibroblasts and 3T3-L1 pre-adipocytes display enhanced adipocyte differentiation that is dependent on the elevated mTORC1 activity in these cells.

Given the previous studies demonstrating that rapamycin could block adipocyte differentiation [11] [16], we hypothesized that the enhanced adipogenesis phenotype of Tsc2−/− MEFs would be dependent on the elevated mTORC1 activity in these cells.

The increase in the fraction of IRES-dependent translation was dependent upon AMPK activity (Figure 7 and Figure 8), and the increased levels of AMPK in the transformed cells were dependent on the elevated c-Src activity in these cells (Figure 6B,C), rather than on the AMP ATP ratio in the cells.

Furthermore, study of Crumley et al (2010) demonstrated that the relation of low albumin concentrations and poorer survival in patients with gastric cancer was dependent on the elevated CRP level.

Studies have established that skeletal muscle wasting may be dependent on the elevated activity of two muscle-specific E3 ligases, atrogin-1 and MuRF1 (muscle RING-finger protein 1), both of which target myofibrillar and intracellular proteins for degradation through the ubiquitin proteasome system [ 5– 8].

Since 15d-PGJ2 arises non-enzymatically from PGD2 [41], [41] the elevated synthesis of this prostanoid is in turn dependent on the elevation of PGD2.

The TRPV1 antagonist JNJ-17203212 also had a dose-dependent effect on the elevated c-fos expression that occurred after intracisternal injection of IS (Fig. 1c).

This is consistent with the expectation that formation of libethenite, a relatively unusual corrosion product, would normally be dependent on the presence of elevated environmental levels of phosphate ions, assuming that there is no internal source in the bronze.

We have previously shown that RNAi- and antisense-mediated FLIP downregulation induces apoptosis in NSCLC cell lines in vitro and in vivo and that the sensitivity of NSCLC cells to FLIP downregulation is dependent on their elevated expression of procapase-8.

Importantly, we show that BRCA1-deficient cancer cells are selectively dependent on their elevated EZH2 levels.