Sentence examples for dependent on pathway from inspiring English sources

We did not observe a change in Evc or Evc2 localization in MC3T3 and IMCD3 cells after treatment with purmorphamine (results not shown) which suggests that cilia localization of Evc and Evc2 is not dependent on pathway activation status.

Additionally, the lack of changes in mitochondrial morphology (i.e. cristae) during acute exposure to Tat in our in vitro model, suggests that this phenomenon is dependent on pathways that subserve an inflammatory response only present in an in vivo milieu.

Thus, senescent cells may be more dependent on pathways that protect against metabolically induced apoptosis than are nonsenescent cells.

Fungal MDSC induction is further dependent on pathways downstream of Dectin-1 signaling, notably reactive oxygen species (ROS) generation as well as caspase-8 activity and interleukin-1 (IL-1) production.

Antibiotic production in Streptomyces sp. (like Mycobacterium sp., a genus of the phylum Actinobacteria) is fundamentally dependent on pathways activated by the bacterial alarmones, guanosine tetraphosphate and guanosine pentaphosphate (commonly designated as (p ppGpp).

These observations suggest that RAMP-mediated apoptosis in gastric cancer cells is dependent on p53 pathway or at least partly dependent on p21 pathway.

In addition, we show that B. burgdorferi-induced murine Lyme arthritis is less dependent on NOD1/NOD2/RICK pathways while the TLR2-MyD88 pathway is crucial.

The caudal dysgenesis in acd mice is also dependent on p53 pathway [38].

The mood stabilizer lithium was shown to induce adult hippocampal progenitors to become neurons dependent on Wnt pathway components such as an elevation of Ctnnb1 [85], [85].

The results show that Akt inhibition represents a promising strategy for the treatment of the breast cancers that are dependent on this pathway.

A variety of molecular techniques and tissue culture and in vivo xenograft models revealed that tumors with mutational activation of Akt signaling were selectively dependent on the pathway.