These results suggest that the effects of hypercapnic acidosis on the NF-κB pathway may be complex and dependent on the milieu of unstable intermediates created by the interactions between hydrogen ions and CO2.
Macrophages play crucial roles in atherosclerosis and immunity [ 17, 18] and are uniquely dependent on the milieu to which they are exposed [ 19], which, as already mentioned, can in turn be modified by OCs [ 5, 6, 9- 13, 14] 14].
The success of treatment for addiction is particularly dependent on the social milieu of the addicted individual, Dr. Volkow said.
Under this hypothesis, the effects of mechanical ventilation would be entirely dependent on the environmental milieu.
Although the FER reflects particle size distribution in HDL and LDL [48], [113], and is dependent on the metabolic milieu and distribution of lipoproteins [48].
The latter study indicated that, in particular, the anabolic response in chondrocytes to IGF was dependent on the cytokine milieu [ 27].
No difference in FSTL1 levels was seen in FLSs (data not shown), suggesting that FSTL1 production in FLSs is dependent on an inflammatory milieu.
Thus, we explored a potential role for polarizing cytokines in promoting IL-17 production in SLE, because the development of Th subsets is critically dependent on the cytokine milieu.
The development of Th17 cells is critically dependent on the cytokine milieu, with IL-1β, TGF-β, IL-6, IL-21, and IL-23 promoting Th17-cell differentiation and expansion [ 29- 34].
Whereas the latter study suggested TCC dechlorination in estuarine environments was highly dependent on the local milieu and microbial community, a recent study documented less-chlorinated congeners of TCC to be ubiquitous in WWTP-impacted freshwater sediments.
