In contrast, the GI neuron, active under hypoglycemic conditions, may be dependent on alterations in intracellular AMPK activity that, in turn, may act via NO to alter neuronal firing rates.
Similarly, specific effects of anions on the receptors for strychnine13 and GABA14 are correlated with observations that the neurophysiological action of these receptors is dependent on alterations in chloride ion conductance15,16.
Our observations lead to the conclusion that different tumorigenic hepatic cell lines possess mechanisms of rapamycin resistance that are not dependent on alterations in the direct actions of mTOR on its targets.
The influx of free fatty acids into intestinal epithelial cells is strongly dependent on alterations in intracellular pH which is regulated by the interplay of PEPT-1 and the sodium-proton exchanger NHX-2.
Tumour development is dependent on alterations in regulatory circuits that govern normal cell proliferation and apoptosis.
21 The changes in the almond texture are dependent on alterations in the microstructure that take place during the roasting and digestion process.
Thus, more recently the Cambridge group reported that the ICP wave amplitude of NPH patients was less dependent on alterations in arterial CBV [ 18].
Consistent with this, our results suggest that, for mild and time-controlled perturbation of Wnt signaling, the effects on the wavefront are not primarily dependent on alterations in Fgf signaling.
In the majority of cases, the processes underlying the global stress response of bacteria are dependent on alterations in gene expression, usually controlled at the transcriptional level by various sigma factors [ 40].
Tissue invasion and metastasis are highly dependent on alterations in the extra-cellular matrix [ 8] and cell-cell interactions that, in part, involve structural changes in cell surface components, including glycosylation (for a review, see [ 9]).
